PDL Treatment

PDL | Laser Surface Treatment


 

PDL_half_implant

PDL | Laser Surface Treatment
Biomate laser surface treatment is a type of thermal processing technique, which applies high energy density laser (up to 1700 ゚C ), focusing on the metal surface to fuse and evaporate the surface with heat.
This technique can form unique 3D pores with micro-nano & microchannel texture on the implant surface, suitable for the adhesion and growth of osteocytes that help increase the contact surface area of the bone and fixture, optimizing the effect of cell proliferation and osseointegration.


treatment comparison of SLA,RBM,PDL
 
No residues of harmful substances on the surface. It is the cleanest implant surface in the world
 
Energy focused on one spot. It is rapid, extremely clean, and suitable for the selective modification of surfaces and allows the generation of complex microstructures/ features with high resolution. These advantages make the technique interesting for geometrically complex biomedical implants. The only residues on BiomateSwiss implants are Ti, N, O, C. The implants on the market have residues of various elements. Titanium is an element that has been scientifically proven to be beneficial to osseointegration. The analysis of chemical bond by National Chung Shing University, Taiwan shows :

Biomate LASER MODIFIED MICRO- AND NANO-  STRUCTURED SURFACE
 
Laser creates a thicker oxide layer
 
The laser produces an oxide layer called TiO2, which is formed on the surface of the pure titanium when contacting oxygen.
The TiO2 layer with anatase texture can effectively increase the adhesion of protein. Studies show that the oxide layer on the
titanium surface can optimize the adhesion and regeneration of blood and osteocyte. National Chung Hsing University, Taiwan, conducted this SEM analysis.


BiomateSWISS-SEM analysis
                              Top of Groove (ridge area): 110nm   Bottom of Groove: 45nm
TEM_analysis
                                                             Bottom of Groove: 45nm
TEM_analysis-2
                                                       Top of Groove (ridge area): 110nm
 
Laser creates 3D pore and MicroChannel
 
First, Biomate patented Precision Dimensional Laser (PDL) creates a unique microchannel with a micro-nano complex 3D pore.
The microchannel induced the precursor of osteoblast directional moving onto the implant surface, and the micro-nano
3D pore improved the efficiency of osteoblast adherence, proliferation, differentiation, and finally, bone formation.
This structure increases the contact surface area of the bone and fixture and optimizes the effect of cell proliferation
and osseointegration. Taipei Medical University conducted this study.




Enhancing osseointegration
 
Mahidol University conducted a study designed to analyze the surface chemistry and topography of laser-irradiated Titanium implants and evaluate the cell morphology and cell adhesion of Human Fetal Osteoblasts(HFOB) seeded on the implants. HFOB cell adhesion is possible after 48 hours in laser-irradiated titanium.
However, the lack of cell maturity and cell adhesion in Biohorizons samples is still unknown. The presence of organic particles on the BIOMATE implants did not deter cell maturation in this in-vitro experiment.

 

PDL laser-treated implant reveals more MSCs attachment and more angiogenesis
 
Assistant Prof. Dr. Yuh presented that PDL laser-treated implant reveals more MSCs attachment and more angiogenesis.
The precision dimension laser (PDL) treated titanium surface shows higher affinity for periodontal stromal cells and induces better peri-implant angiogenesis ex vivo.  This unique anglophilic surface treatment developed by Biomate may provide better peri-implant treatment outcomes for the aging population.
Please refer to the attachment.


PDL_MSCs

 
The constructure of the surface is very firm

According to a pilot study conducted by Mahidol University, Biomate plus presented only a few damages over the implant.
The damage could be found as chipping, pit, and flattening.  SLA implant presented pit, flattening, and fuse surface in larger
amount compared to Biomate Plus.  
The defect could be easily found especially in apical thread corresponding to self-tapping design.  
Biomate plus surface did not present the sharp asperities in micro level, therefore this might be the reason why it had minimal
surface alteration and more durable properties.  Therefore, the macro-nano roughness is not easy to be damaged at the high
torque force.  
It demonstrates that the constructure of the surface is very firm.

 
PDL Laser Surface Treatment SLA Surface Treatment
5μm
 
At 100x magnification, the SLA surface shows
homogeneous cobweb-like pattern.
At 500x magnification, the surface shows
the homogeneous pattern which the top shows
mild roughness formed with pebble shape area,
the cliff shows multiple pebble-like and the
the bridge connects between each hill and the
the deepest part of the valley could not be reached with
SEM.
At 2000x magnification, the surface presents
multiple sharp spikes and round pits spreading
in a random pattern.




 
The crest of the thread shows chipping but
underneath those area, the roughness
pattern still can be found.
At 2000x magnification, the spikes were
compressed into flat area.
 
The chipping also can be found in flat area
which disrupts the continuity of the pattern
and the titanium surface seems a little bit
more flattening.
At 500x magnification, the pit, pore and
the elevation is found at the top of thread.

 

 



The best Hemocompatibility

 
Fixture with Hemocompatible surface improves the adhesion of protein in the blood, increasing the coagulation of blood.
PDL Laser-treated implant shows hemocompatible characteristics. Some scholars said that hemocompatible fixture is beneficial
to cell proliferation and differentiation, improving the growth of osteocytes.
Contact Angle of Blood
BiomateSWISS Fixture with hemocompatible surface improves the adhesion of protein in the blood, increasing the coagulation of blood.

Blood testing (Dripping)
Due to the experiment of contact angle of blood,
it shows the contact angle of blood in BiomateSwiss is 0°.


Video of Biomate Implant-Blood Affinity Test



 

Higher BIC (Bone to Implant Contact) rate
 
PDL Surface treatment applies precise parametric design. Through high efficacy laser luminous energy to strike qualitative micro-nano,
complex 3D texture that helps increase the contact surface area of the bone and fixture optimizes the effect of cell proliferation and
osseointegration.

RIC_rate

The Best Anti-Inflammatory

Chung Shan University has conducted research to find that bacterial on the complex structure can be cleaned by the combination therapy
of Er: YAG laser and aPDT system can clean deeply and efficiently into microchannels for both SLA and PDL surface without altering the surface architecture, could be a useful cleaning method for peri-implantitis therapy, especially for a nano microtextured surface.
In addition, this research finds that bacterial, A. actinomycetemcomitans, attached to the deep site of the complex 3D structure is not a big difference between 4 hours an d48 hours.  
It also shows that A. sctinomycetemcomitans doesn’t attach to the laser surface as much as on SLA surface.  A. actinomycetemcomitans cause
peri-implantitis.

 
A.actinomycetemcomitans
SLA PDL surface
6h 6h
48h 48h


 
Laser-treated surfaces showed the lowest biofilm formation
 
We worked with Milano University, Italy in 2019. The research title is, "Laser micro texturing of titanium implant surfaces to reduce oral biofilm formation." Because of COVID19, this research has been delayed. On September 16-18, 2021, the researcher Dr. Anderi Ionescu has just been presenting at the hybrid meeting of the Continental European Division of the International Association for Dental Research with most of this data on September 16, 2021. His research demonstrates that “Laser micro texturing of titanium surfaces created surface micro topographies and also influenced surface chemical composition. Both (Geass and Biomate) macrotextures were equally effective in reducing biofilm formation." From 48 hours viable oral microcosm (optical density units) we can see Biomate is much less than Geass because of the different surface structure“ Please refer to his poster,

Laser microtexturing of titanium surfaces for reduced oral biofilm formation

 
Biomate implant is very suitable for Immediate replacement & loading
 
A preliminary study at the master program of oral implantology Cairo University conducted by Refky A, and Elkhadem A and presented on Bangkok International Dental Implant Symposium 2019, “The impact of PDL versus RBM implant surface treatment on implant stability during healing: A preliminary clinical study Aim: Compare changes in ISQ values of PDL versus RBM surfaces during the healing period.” This study finds that: Conventional sandblasted implant surfaces show implant stability dip from week 2-6 while PDL implants show gradual increase instability throughout the healing phase. Please refer to the attached studies.

ISQ Changes during 8 weeks healing


After this preliminary, Prof. Dr. Amr conducted a clinical study and presented the result on June 6, 2021, "Implant Stability Changes for PDL Versus SLA Treated Surfaces in Immediate Extraction Cases: A Randomized Controlled Clinical Trial." This study finds that 1. Laser treatment of the implant surface seems to be a promising approach to promote faster bone healing, 2 PDL implant maintained higher implant stability levels in immediate implants compared to SLA, and 3. PDL implant can be a game-changer in immediate extraction sockets. Please refer to the attached studies.
RFA in Laser Treatment